The Division of Neonatology at UCSF is committed to innovation of clinical practice and excellence in patient care that has distinguished the program since its inception by Drs. Bill Tooley and Roderic Phibbs more than 40 years ago. The William H. Tooley Intensive Care Unit was established at UCSF in 1964 to create a highly specialized clinical environment to tackle the problem of respiratory distress syndrome, then the predominant cause of neonatal mortality in the developed world. Four decades of basic and translational research and continuous refinement of our multi-disciplinary approach to clinical care has had a dramatic impact on the survival of premature infants here, within the region we serve, and around the world.